ea0007p5 | Bone | BES2004
White H
, Ahmad A
, Joseph F
, Prabhakar V
, Patwala A
, Whittingham P
, Durham B
, Fraser W
, Vora J
Adult Growth Hormone Deficiency (AGHD) is associated with osteoporosis. PTH circadian rhythmicity is important for bone remodelling. Abnormalities in PTH circadian rhythms, including a blunted nocturnal rise, have been reported in AGHD and may contribute to osteoporosis development. GH replacement (GHR) results in improvement of PTH circadian rhythmicity and bone mineral density (BMD). In health, increasing age is associated with declining GH secretion and the appropriateness ...